BDBM442783 7-({(1R)-1-[3-Fluoro-4-(trifluoromethyl)phenyl]-2,2-dimethylpropyl}amino)-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile::US10647727, Example 40

SMILES Cc1cc(N[C@@H](c2ccc(c(F)c2)C(F)(F)F)C(C)(C)C)n2ncc(C#N)c2n1

InChI Key InChIKey=SLTDLLLOGAFJNA-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442783   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM442783(US10647727, Example 40 | 7-({(1R)-1-[3-Fluoro-4-(t...)Copy SMILESCopy InChI

Affinity DataKi:  462nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/25/2021
Entry Details
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