BDBM442780 N-(1-(3-Fluoro-4-(trifluoromethyl)phenyl)cyclopropyl)-2,9-dimethyl-9H-purin-6-amine::US10647727, Example 37

SMILES Cc1nc(NC2(CC2)c2ccc(c(F)c2)C(F)(F)F)c2ncn(C)c2n1

InChI Key InChIKey=CEUOXCQXXWFIBY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442780   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM442780(US10647727, Example 37 | N-(1-(3-Fluoro-4-(trifluo...)
Affinity DataKi:  115nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2021
Entry Details
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