BDBM442773 1,6-Dimethyl-4-({1-[4-(trifluoromethyl)phenyl]cyclopropyl}oxy)-1H-pyrazolo[3,4-d]pyrimidine::US10647727, Example 30

SMILES Cc1nc(OC2(CC2)c2ccc(cc2)C(F)(F)F)c2cnn(C)c2n1

InChI Key InChIKey=FTJMFBSGBBNUQO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442773   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM442773(US10647727, Example 30 | 1,6-Dimethyl-4-({1-[4-(tr...)
Affinity DataKi:  32nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2021
Entry Details
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