BDBM442769 N,1,6-Trimethyl-N-{1-[4-(trifluoromethyl)phenyl]cyclopropyl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine::US10647727, Example 26

SMILES CN(c1nc(C)nc2n(C)ncc12)C1(CC1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=RXYPDPYUAIBWIJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442769   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM442769(US10647727, Example 26 | N,1,6-Trimethyl-N-{1-[4-(...)
Affinity DataKi:  4.90nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2021
Entry Details
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