BDBM441970 US10647700, Compound 24

SMILES CCN(C(=O)C1CCCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCN(CC2)C(=O)OC(C)(C)C)cc1

InChI Key InChIKey=QRPDMFPDXYQBDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441970   

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441970(US10647700, Compound 24)
Affinity DataIC50: 16nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent