BDBM441964 US10647700, Compound 18

SMILES CCN(C(=O)C1CCCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(nc1)N1CCN(CC1)C(C)C

InChI Key InChIKey=BYPQFKALRUEKPJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441964   

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent

LigandBDBM441964(US10647700, Compound 18)Copy SMILESCopy InChI

Affinity DataIC50: 515nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/25/2021
Entry Details
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