BDBM441935 US10647694, Example 23

SMILES COc1cc(C2CCNCC2)c(cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)C#N

InChI Key InChIKey=NBJWDSRVPLSYCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441935   

TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM441935(US10647694, Example 23)
Affinity DataIC50: 5.5nMAssay Description:The in-vitro kinase assay was performed using the HTRF kinEASE TK kit available from Cisbio. The operation steps are indicated in the instructions of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent