BDBM441846 US10647665, Example 1-32::US10647665, Example 1-33::US10647665, Example 1-34::US10647665, Example 1-35::US10647665, Example 1-36::US10647665, Example 1-37::US10647665, Example 1-38+++::US10851050, Example I-1

SMILES CCS(=O)(=O)c1ccc(CNC(=O)Nc2cc(Cl)c(c(Cl)c2)-c2ccccc2OC(F)(F)F)cc1

InChI Key InChIKey=JSCWNFIGCHHELZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 441846   

TargetNuclear receptor ROR-gamma(Human)
Fudan University

US Patent
LigandPNGBDBM441846(US10647665, Example 1-35 | US10647665, Example 1-3...)
Affinity DataIC50: 500nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Fudan University

US Patent
LigandPNGBDBM441846(US10647665, Example 1-35 | US10647665, Example 1-3...)
Affinity DataIC50: 500nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Fudan University

US Patent
LigandPNGBDBM441846(US10647665, Example 1-35 | US10647665, Example 1-3...)
Affinity DataIC50: 500nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Fudan University

US Patent
LigandPNGBDBM441846(US10647665, Example 1-35 | US10647665, Example 1-3...)
Affinity DataIC50: 500nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Fudan University

US Patent
LigandPNGBDBM441846(US10647665, Example 1-35 | US10647665, Example 1-3...)
Affinity DataIC50: 2.75E+3nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Fudan University

US Patent
LigandPNGBDBM441846(US10647665, Example 1-35 | US10647665, Example 1-3...)
Affinity DataIC50: 500nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Fudan University

US Patent
LigandPNGBDBM441846(US10647665, Example 1-35 | US10647665, Example 1-3...)
Affinity DataIC50: 500nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Fudan University

US Patent
LigandPNGBDBM441846(US10647665, Example 1-35 | US10647665, Example 1-3...)
Affinity DataIC50: 500nMAssay Description:The inhibitory activity of compounds on RORγ receptor was determined by fluorescence resonance energy transfer (FRET) experiments. The inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2021
Entry Details
Go to US Patent