BDBM441779 US10640533, Identification number CX13-133::US10640533, Table 1.26

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccncc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)Cc1ccc(CN2CCOCC2)cc1)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=IRAOTOKFIWRLCT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 441779   

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandPNGBDBM441779(US10640533, Table 1.26 | US10640533, Identificatio...)
Affinity DataIC50: 4.65nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetProteasome subunit beta type-1(Human)
Centrax International

US Patent
LigandPNGBDBM441779(US10640533, Table 1.26 | US10640533, Identificatio...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetTransmembrane protease serine 11D(Human)
Centrax International

US Patent
LigandPNGBDBM441779(US10640533, Table 1.26 | US10640533, Identificatio...)
Affinity DataIC50: 455nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandPNGBDBM441779(US10640533, Table 1.26 | US10640533, Identificatio...)
Affinity DataIC50: 3.58nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetProteasome subunit beta type-1(Human)
Centrax International

US Patent
LigandPNGBDBM441779(US10640533, Table 1.26 | US10640533, Identificatio...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetTransmembrane protease serine 11D(Human)
Centrax International

US Patent
LigandPNGBDBM441779(US10640533, Table 1.26 | US10640533, Identificatio...)
Affinity DataIC50: 443nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent