BDBM441114 US10640495, Example I-329

SMILES COCC[C@@H]1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2)-c2cnc3N(C)C(=O)Cc3c2)[C@@H](O1)c1ccnc(F)c1

InChI Key InChIKey=CBUJIPKDBHUPFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441114   

TargetHigh affinity nerve growth factor receptor(Human)
Shionogi

US Patent
LigandPNGBDBM441114(US10640495, Example I-329)
Affinity DataIC50: 1.70nMAssay Description:Seven point five μL per well of human TrkA (PV3144, Lifetechnologies, final concentration: 1 nmol/L) suspended in the assay buffer (100 mmol/L 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent