BDBM441095 US10640495, Example I-253

SMILES CNC(=O)c1ncc(cc1C)-c1nn(c(NC(=O)N[C@@H]2CN(CCOC)O[C@H]2c2cnc(F)c(F)c2)c1C)-c1ccccc1

InChI Key InChIKey=QJOBFFLKJSZQIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441095   

TargetHigh affinity nerve growth factor receptor(Human)
Shionogi

US Patent
LigandPNGBDBM441095(US10640495, Example I-253)
Affinity DataIC50: 1.30nMAssay Description:Seven point five μL per well of human TrkA (PV3144, Lifetechnologies, final concentration: 1 nmol/L) suspended in the assay buffer (100 mmol/L 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent