BDBM441 5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)ethyl]-6-methyl-2-oxo-5,6-dihydro-2H-pyran-3-yl}sulfanyl)-2-methylphenyl 1-methyl-1H-imidazole-2-sulfonate::Dihydropyran-2-one deriv. 46

SMILES Cc1cc(SC2C(=O)CC(C)(CCc3ccc(O)cc3)OC2=O)c(cc1OS(=O)(=O)c1nccn1C)C(C)(C)C

InChI Key InChIKey=XTVVMXWFFSPMKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM441(5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...)
Affinity DataIC50: 2nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2004
Entry Details Article
PubMed