BDBM440743 (-)-2-Fluoro-4-(trifluoromethoxy)benzyl 2-(4,5,6,7-tetrahydro-1H-benzo[d][1,2,3] triazole-5-carbonyl)-2,7-diazaspiro[3.5]nonane-7-carbox::US10633384, Example 15B

SMILES Fc1cc(OC(F)(F)F)ccc1COC(=O)N1CCC2(CN(C2)C(=O)[C@@H]2CCc3[nH]nnc3C2)CC1

InChI Key InChIKey=AJEXTHORZPSOBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 440743   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM440743((-)-2-Fluoro-4-(trifluoromethoxy)benzyl 2-(4,5,6,7...)
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
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Date in BDB:
1/12/2021
Entry Details
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