BDBM440712 US10639284, Compound 2.063::US11426364, Compound 2.063

SMILES OP(O)(=O)CNCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2ccccc2F)cc1OCc1cncc(c1)C#N

InChI Key InChIKey=LXXXFIYAYZWZES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 440712   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM440712(US10639284, Compound 2.063 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4 ° C. The wells were then blocked with PBS containing 2% BSA i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM440712(US10639284, Compound 2.063 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent