BDBM43962 5-(4-benzyl-1-piperazinyl)-2-(2-thienyl)-1,3-oxazole-4-carbonitrile::5-(4-benzylpiperazin-1-yl)-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile::5-(4-benzylpiperazino)-2-(2-thienyl)oxazole-4-carbonitrile::5-[4-(phenylmethyl)-1-piperazinyl]-2-thiophen-2-yl-4-oxazolecarbonitrile::5-[4-(phenylmethyl)piperazin-1-yl]-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile::MLS000088920::SMR000073154::cid_1978771

SMILES N#Cc1nc(oc1N1CCN(Cc2ccccc2)CC1)-c1cccs1

InChI Key InChIKey=DKOVEXNOIZABKV-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 43962   

TargetSolute carrier family 12 member 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM43962(5-[4-(phenylmethyl)-1-piperazinyl]-2-thiophen-2-yl...)
Affinity DataEC50:  1.17E+4nMAssay Description:Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2011
Entry Details
PCBioAssay
TargetSolute carrier family 12 member 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM43962(5-[4-(phenylmethyl)-1-piperazinyl]-2-thiophen-2-yl...)
Affinity DataEC50:  3.58E+3nMAssay Description:Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2011
Entry Details
PCBioAssay
TargetSolute carrier family 12 member 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM43962(5-[4-(phenylmethyl)-1-piperazinyl]-2-thiophen-2-yl...)
Affinity DataEC50:  4.16E+3nMAssay Description:Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43962(5-[4-(phenylmethyl)-1-piperazinyl]-2-thiophen-2-yl...)
Affinity DataIC50: 849nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay