BDBM439580 4-[4′,4′-difluoro-4-(2-hydroxypropan-2-yl)[2′,3′,4′,5′-tetrahydro[1,1′-biphenyl]]-2-yl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide::US10633379, Example 111

SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1C1=CCC(F)(F)CC1)C(C)(C)O

InChI Key InChIKey=HNKDFACMTGAUAI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439580   

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandPNGBDBM439580(US10633379, Example 111 | 4-[4′,4′-dif...)
Affinity DataKi:  1.40nMAssay Description:Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandPNGBDBM439580(US10633379, Example 111 | 4-[4′,4′-dif...)
Affinity DataKi:  150nMAssay Description:Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
Go to US Patent