BDBM43950 8-{[1-(6-bromo-1,3-benzothiazol-2-yl)piperidin-4-yl]carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane::MLS000093672::SMR000029290::[1-(6-bromanyl-1,3-benzothiazol-2-yl)piperidin-4-yl]-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methanone::[1-(6-bromo-1,3-benzothiazol-2-yl)-4-piperidinyl]-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methanone::[1-(6-bromo-1,3-benzothiazol-2-yl)-4-piperidyl]-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methanone::[1-(6-bromo-1,3-benzothiazol-2-yl)piperidin-4-yl]-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methanone::cid_3241401

SMILES Brc1ccc2nc(sc2c1)N1CCC(CC1)C(=O)N1CCC2(CC1)OCCO2

InChI Key InChIKey=PUYUEZYEZDGPGV-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 43950   

TargetSignal transducer and activator of transcription 3 [702-738,740-752](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43950(8-{[1-(6-bromo-1,3-benzothiazol-2-yl)piperidin-4-y...)
Affinity DataIC50: 2.79E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43950(8-{[1-(6-bromo-1,3-benzothiazol-2-yl)piperidin-4-y...)
Affinity DataIC50: 5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetSolute carrier family 12 member 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM43950(8-{[1-(6-bromo-1,3-benzothiazol-2-yl)piperidin-4-y...)
Affinity DataEC50:  1.43E+4nMAssay Description:Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2011
Entry Details
PCBioAssay
TargetSolute carrier family 12 member 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM43950(8-{[1-(6-bromo-1,3-benzothiazol-2-yl)piperidin-4-y...)
Affinity DataEC50:  7.02E+3nMAssay Description:Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2011
Entry Details
PCBioAssay
TargetSolute carrier family 12 member 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM43950(8-{[1-(6-bromo-1,3-benzothiazol-2-yl)piperidin-4-y...)
Affinity DataEC50:  5.25E+3nMAssay Description:Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay