BDBM439373 (S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)-3-(3-methoxyphenyl)propanamido)benzoic acid::US10633375, Compound No. 72::US11084808, Compound 72

SMILES COc1cccc(C[C@@H](C(=O)Nc2ccc(cc2)C(O)=O)n2cc(OC)c(cc2=O)-c2cc(Cl)ccc2C(C)=O)c1

InChI Key InChIKey=RUHVPRDOPLXPTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439373   

TargetCoagulation factor XI(Human)
Jinagsu Hengrui Medicine

US Patent
LigandPNGBDBM439373((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 21nMAssay Description:Test Example 1: Biological Activity of the Compounds of the Present Invention onThe Inhibition of Factor XIa Detected by Absorption Photometry1. Expe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
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TargetCoagulation factor XI(Human)
Jinagsu Hengrui Medicine

US Patent
LigandPNGBDBM439373((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 21nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent