BDBM439349 (S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)-3-phenylpropanamido)-N-ethylbenzamide::US10633375, Compound No. 37::US11084808, Compound 37

SMILES CCNC(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)n2cc(OC)c(cc2=O)-c2cc(Cl)ccc2C(C)=O)cc1

InChI Key InChIKey=MCFUOYLOPZXRIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439349   

TargetCoagulation factor XI(Human)
Jinagsu Hengrui Medicine

US Patent
LigandPNGBDBM439349((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 29nMAssay Description:Test Example 1: Biological Activity of the Compounds of the Present Invention onThe Inhibition of Factor XIa Detected by Absorption Photometry1. Expe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jinagsu Hengrui Medicine

US Patent
LigandPNGBDBM439349((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 29nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent