BDBM438926 US10604489, Compound 87::US11180455, Compound 89

SMILES COC1(C2CCCC1CN(C2)C1C[C@@H](C1)c1ccccc1)c1ccnc(c1)C(N)=O

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 438926   

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM438926(US10604489, Compound 87 | US11180455, Compound 89)
Affinity DataKi: <1nMAssay Description:Membrane protein from CHO (Chinese Hamster Ovarian) cells that stably expressed one type of the cloned human opioid receptor were incubated with 12 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM438926(US10604489, Compound 87 | US11180455, Compound 89)
Affinity DataKi: <1nMAssay Description:The Ki (binding affinity) for μ-receptor was determined with a previously described method using a competitive displacement assay (Neumeyer et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM438926(US10604489, Compound 87 | US11180455, Compound 89)
Affinity DataKi: <1nMAssay Description:The Ki (binding affinity) for μ-receptor was determined with a previously described method using a competitive displacement assay (Neumeyer et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
Go to US Patent