BDBM438893 (1R,5S)-3-cyclopentyl-3-azaspiro[bicyclo[3.3.1]nonane-9,2′-[1,3]dioxolane]::US10604489, Compound 55::US11180455, Compound 55

SMILES COC1(C2CCCC1CN(C2)C1CCCC1)c1ccnc(c1)C(N)=O

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438893   

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM438893((1R,5S)-3-cyclopentyl-3-azaspiro[bicyclo[3.3.1]non...)
Affinity DataKi: <1nMAssay Description:Membrane protein from CHO (Chinese Hamster Ovarian) cells that stably expressed one type of the cloned human opioid receptor were incubated with 12 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
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TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM438893((1R,5S)-3-cyclopentyl-3-azaspiro[bicyclo[3.3.1]non...)
Affinity DataKi: <1nMAssay Description:The Ki (binding affinity) for μ-receptor was determined with a previously described method using a competitive displacement assay (Neumeyer et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
Go to US Patent