BDBM438801 4-(2-(2-((3'-(5-(4- carboxyphenethyl)-1- methyl-4,5,6,7-tetrahydro- 1H-imidazo[4,5-c]pyridine- 2-carboxamido)-2-chloro-2'- methyl-[1,1'-biphenyl]-3- yl)carbamoyl)-1-methyl- 1,4,6,7-tetrahydro-5H- imidazo[4,5-c]pyridin-5- yl)ethyl)bicyclo[2.2.1] heptane-1-carboxylic acid::US10618916, Example 36::US10906920, Example 36::US11414433, Example 36

SMILES Cc1c(NC(=O)c2nc3CN(CCc4ccc(cc4)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

InChI Key InChIKey=ZIANCQKLZJPIHJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 438801   

LigandPNGBDBM438801(4-(2-(2-((3'-(5-(4- carboxyphenethyl)-1- methyl-4,...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
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LigandPNGBDBM438801(4-(2-(2-((3'-(5-(4- carboxyphenethyl)-1- methyl-4,...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438801(4-(2-(2-((3'-(5-(4- carboxyphenethyl)-1- methyl-4,...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent