BDBM438310 4-Chloro-5-fluoro-1-(2-((3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-2-oxoethyl)-1′-(1H-pyrazolo[4,3-b]pyridine-5-carbonyl)spiro[indoline-3,4′-piperidin]-2-one::US10618897, Example 131

SMILES Fc1ccc2N(CC(=O)N3C[C@@H]4CCC[C@@H]4C3)C(=O)C3(CCN(CC3)C(=O)c3ccc4[nH]ncc4n3)c2c1Cl

InChI Key InChIKey=RVDJTOVZNIMOGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438310   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438310(4-Chloro-5-fluoro-1-(2-((3aR,6aS)-hexahydrocyclope...)
Affinity DataIC50: 23.7nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
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Date in BDB:
12/20/2020
Entry Details
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