BDBM438295 US10618897, Example 116::US10618897, Example 117

SMILES Fc1ccc2N(CC(=O)N3CCOC(C3)C(F)(F)F)C(=O)C3(CCN(CC3)C(=O)c3ccc4[nH]ncc4n3)c2c1Cl

InChI Key InChIKey=LBUNLXUVXFFNHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438295   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438295(US10618897, Example 117 | US10618897, Example 116)
Affinity DataIC50: 59.7nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438295(US10618897, Example 117 | US10618897, Example 116)
Affinity DataIC50: 42nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent