BDBM43816 5'-bromanylspiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3'-1H-indole]-2'-one::5'-bromo-2'-spiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3'-1H-indole]one::5'-bromospiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3'-1H-indole]-2'-one::5'-bromospiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3'-indoline]-2'-one::MLS-0258268.0001::cid_4879298

SMILES Brc1ccc2NC(=O)C3(NNc4ccccc4O3)c2c1

InChI Key InChIKey=LPLIRDQZBOMOQI-UHFFFAOYSA-N

Data  9 IC50  11 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 43816   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50:  892nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
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In Depth
Date in BDB:
7/8/2011
Entry Details
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TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 1.18E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/TrEMBL
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In Depth
Date in BDB:
1/4/2012
Entry Details
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TargetToll-like receptor 9(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 1.31E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Date in BDB:
1/4/2012
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TargetEndoribonuclease toxin MazF(Escherichia coli (strain K12))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50: >9.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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In Depth
Date in BDB:
1/5/2012
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TargetEndoribonuclease toxin MazF(Escherichia coli (strain K12))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50:  7.31E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
1/5/2012
Entry Details
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TargetIntestinal-type alkaline phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50:  257nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
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In Depth
Date in BDB:
8/1/2011
Entry Details
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TargetAlkaline phosphatase, germ cell type(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50:  550nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
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In Depth
Date in BDB:
8/1/2011
Entry Details
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TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50:  454nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
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In Depth
Date in BDB:
8/1/2011
Entry Details
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TargetIntestinal-type alkaline phosphatase 1(Rat)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 8.09E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
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In Depth
Date in BDB:
8/1/2011
Entry Details
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TargetIntestinal-type alkaline phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50:  1.01E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
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In Depth
Date in BDB:
7/31/2011
Entry Details
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TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50: <195nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
5/21/2011
Entry Details
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TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50:  848nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
5/31/2011
Entry Details
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TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50:  227nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
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In Depth
Date in BDB:
5/31/2011
Entry Details
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TargetGlutathione S-transferase Mu 1(Human)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataEC50:  2.38E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
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In Depth
Date in BDB:
5/29/2011
Entry Details
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TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
5/28/2011
Entry Details
Copy Entry DOIPCBioAssay
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TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
5/28/2011
Entry Details
Copy Entry DOIPCBioAssay
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TargetAlkaline phosphatase, germ cell type(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
5/28/2011
Entry Details
Copy Entry DOIPCBioAssay
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TargetAlkaline phosphatase, germ cell type(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
5/28/2011
Entry Details
Copy Entry DOIPCBioAssay
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TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
5/28/2011
Entry Details
Copy Entry DOIPCBioAssay
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TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM43816(cid_4879298 | 5'-bromanylspiro[1,2-dihydro-4,1,2-b...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
5/28/2011
Entry Details
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