BDBM438119 US10618886, Compound XII::US11420955, Compound XII

SMILES COc1cc(OCCCN2CCC(C)C2)ccc1-n1c(C)nc2ccc(cc2c1=O)S(F)(F)(F)(F)F

InChI Key InChIKey=QWTSDSBEFRRDDA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 438119   

TargetHistamine H3 receptor(Human)
Xw Laboratories

US Patent
LigandPNGBDBM438119(US10618886, Compound XII | US11420955, Compound XI...)
Affinity DataIC50: 4.97nMAssay Description:Briefly, for membrane parathion, HEK293/Ga15/hH3R cells were grown to confluence, harvested and the cell pellets were suspended in TEL buffer (50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetHistamine H3 receptor(Human)
Xw Laboratories

US Patent
LigandPNGBDBM438119(US10618886, Compound XII | US11420955, Compound XI...)
Affinity DataIC50: 17.6nMAssay Description:Briefly, for membrane parathion, HEK293/Ga15/hH3R cells were grown to confluence, harvested and the cell pellets were suspended in TEL buffer (50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetHistamine H3 receptor(Human)
Xw Laboratories

US Patent
LigandPNGBDBM438119(US10618886, Compound XII | US11420955, Compound XI...)
Affinity DataIC50: 4.97nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetHistamine H3 receptor(Human)
Xw Laboratories

US Patent
LigandPNGBDBM438119(US10618886, Compound XII | US11420955, Compound XI...)
Affinity DataIC50: 17.6nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent