BDBM438100 US10597399, Compound S32

SMILES CC1CN(Cc2nnc(-c3ccccn3)n12)C(=O)c1cc(Cc2n[nH]c(=O)c(C)c2C)ccc1F

InChI Key InChIKey=DESLCYGONMKVQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438100   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM438100(US10597399, Compound S32)
Affinity DataIC50: 100nMAssay Description:The HTb-PARP-1 positive clones were obtained using the full-length PARP-1 plasmid, through PCR amplification, enzyme digestion, ligation, and transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM438100(US10597399, Compound S32)
Affinity DataIC50: 61nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed