BDBM437320 1-methyl-4-(3-methylazetidin-1-yl)-5-(1-(1-phenylethyl)-1H- pyrazol-4-yl)pyridin-2(1H)-one::US10617680, Example 54::US11020380, Example 54

SMILES CC(c1ccccc1)n1cc(cn1)-c1cn(C)c(=O)cc1N1CC(C)C1

InChI Key InChIKey=AGIOEMMQSOYBBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437320   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM437320(1-methyl-4-(3-methylazetidin-1-yl)-5-(1-(1-phenyle...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
Go to US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM437320(1-methyl-4-(3-methylazetidin-1-yl)-5-(1-(1-phenyle...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
Go to US Patent