BDBM437232 1-[2-(3-Fluoroazetidin-1-yl)-2-oxo-ethyl]-6-[5-(trifluoromethyl)-2-thienyl]-3H- imidazo[4,5-b]pyridin-2-one::US10617676, Example 578::US11207298, Example 578

SMILES FC1CN(C1)C(=O)Cn1c2cc(cnc2[nH]c1=O)-c1ccc(s1)C(F)(F)F

InChI Key InChIKey=CUSFQDKHTGPAEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437232   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437232(1-[2-(3-Fluoroazetidin-1-yl)-2-oxo-ethyl]-6-[5-(tr...)
Affinity DataIC50: 14nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
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TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437232(1-[2-(3-Fluoroazetidin-1-yl)-2-oxo-ethyl]-6-[5-(tr...)
Affinity DataIC50: 14nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent