BDBM437218 6-[5-(Difluoromethyl)-2-thienyl]-3-methyl-1-[(5-methylisoxazol-3- yl)methyl]imidazo[4,5-b]pyridin-2-one::US10617676, Example 564::US11207298, Example 564

SMILES O=C(Cc1ccc(C2CC2)cc1F)N1CCN(c2nc3ncc(F)cc3o2)CC1

InChI Key InChIKey=FSNGSSMPTCOCHA-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437218   

TargetPantothenate kinase 3(Human)
St. Jude Children''s Research Hospital, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 437218BDBM437218(US12534451, Compound PZ-4352)
Affinity DataIC50: 0.860nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details US Patent
PDB3D3D Structure (crystal)