BDBM437076 1-(2-(3,3-Difluoroazetidin-1-yl)-2-oxoethyl)-6-(4-fluoro-3-methylphenyl)-3- methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one::US10617676, Example 413::US11207298, Example 413

SMILES Cc1cc(ccc1F)-c1cnc2n(C)c(=O)n(CC(=O)N3CC(F)(F)C3)c2c1

InChI Key InChIKey=NBXNOABBRFBTRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437076   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437076(US10617676, Example 413 | 1-(2-(3,3-Difluoroazetid...)
Affinity DataIC50: 9nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
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TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437076(US10617676, Example 413 | 1-(2-(3,3-Difluoroazetid...)
Affinity DataIC50: 9nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent