BDBM437053 6-(4-Fluoro-3-methyl-phenyl)-3-methyl-1-(2-oxobutyl)imidazo[4,5-b]pyridin- 2-one::US10617676, Example 389::US11207298, Example 389

SMILES CCC(=O)Cn1c2cc(cnc2n(C)c1=O)-c1ccc(F)c(C)c1

InChI Key InChIKey=ULYILMIYKRTPRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437053   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437053(US10617676, Example 389 | 6-(4-Fluoro-3-methyl-phe...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
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TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437053(US10617676, Example 389 | 6-(4-Fluoro-3-methyl-phe...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent