BDBM4369 (3Z)-2-amino-3-[(3-bromo-4,5-dihydroxyphenyl)methylidene]prop-1-ene-1,1,3-tricarbonitrile::benzylidenemalononitrile (BMN) deriv. 53

SMILES Oc1cc(C=C(C#N)C(=N)C(C#N)C#N)cc(Br)c1O

InChI Key InChIKey=GJJNPOJHPLSZEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4369   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4369((3Z)-2-amino-3-[(3-bromo-4,5-dihydroxyphenyl)methy...)
Affinity DataIC50: 500nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4369((3Z)-2-amino-3-[(3-bromo-4,5-dihydroxyphenyl)methy...)
Affinity DataIC50: 500nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed