BDBM436860 N-(3,3-Difluorocyclobutyl)-2-[2-oxo-6-[3-(trifluoromethyl)phenyl]-3H- imidazo[4,5-b]pyridin-1-yl]acetamide::US10617676, Example 195::US11207298, Example 195

SMILES FC(F)(F)c1cccc(c1)-c1cnc2[nH]c(=O)n(CC(=O)NC3CC(F)(F)C3)c2c1

InChI Key InChIKey=JAEZJXWQBMISRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436860   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436860(US10617676, Example 195 | N-(3,3-Difluorocyclobuty...)
Affinity DataIC50: 7nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436860(US10617676, Example 195 | N-(3,3-Difluorocyclobuty...)
Affinity DataIC50: 7nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent