BDBM436770 N,N-Dimethyl-2-[3-methyl-2-oxo-6-[5-(trifluoromethyl)-3- thienyl]imidazo[4,5-b]pyridin-1-yl]acetamide::US10617676, Example 101::US11207298, Example 101

SMILES CN(C)C(=O)Cn1c2cc(cnc2n(C)c1=O)-c1csc(c1)C(F)(F)F

InChI Key InChIKey=CLQCUNFBUZQZHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436770   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436770(US10617676, Example 101 | N,N-Dimethyl-2-[3-methyl...)
Affinity DataIC50: 19nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436770(US10617676, Example 101 | N,N-Dimethyl-2-[3-methyl...)
Affinity DataIC50: 19nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent