BDBM436767 1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-6-[5-(difluoromethyl)-3-thienyl]-3-methyl- imidazo[4,5-b]pyridin-2-one::US10617676, Example 98::US11207298, Example 98

SMILES Cn1c2ncc(cc2n(CC(=O)N2CCC2)c1=O)-c1csc(c1)C(F)F

InChI Key InChIKey=LPHRRZNXDQWBBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436767   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436767(US10617676, Example 98 | 1-[2-(Azetidin-1-yl)-2-ox...)
Affinity DataIC50: 13nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
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TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436767(US10617676, Example 98 | 1-[2-(Azetidin-1-yl)-2-ox...)
Affinity DataIC50: 13nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent