BDBM43654 7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-yldiazane::7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-ylhydrazine::MLS001019034::SMR000363388::cid_722717

SMILES NNc1ncnc2sc3CCCc3c12

InChI Key InChIKey=VZXTYNJVVIGIIQ-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 43654   

TargetSignal transducer and activator of transcription 3 [702-738,740-752](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43654(MLS001019034 | 7,8-dihydro-6H-cyclopenta[4,5]thien...)
Affinity DataIC50: 5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2011
Entry Details
PCBioAssay
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43654(MLS001019034 | 7,8-dihydro-6H-cyclopenta[4,5]thien...)
Affinity DataEC50: >5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2011
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 2(Human)
Universit�� Pierre Et Marie Curie

LigandPNGBDBM43654(MLS001019034 | 7,8-dihydro-6H-cyclopenta[4,5]thien...)
Affinity DataKd:  2.87E+5nMpH: 7.5 T: 2°CAssay Description:We incubated human recombinant CDK2/cyclin A with small molecules at the indicatedconcentrations in buffer A (Tris HCl (25 mm, pH 7.5), MgCl2 (10 mm)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed