BDBM43647 (4E)-4-(1H-indol-2-ylmethylene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one::4-[(Z)-2-indolylidenemethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one::4-[(Z)-indol-2-ylidenemethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one::4-[(Z)-indol-2-ylidenemethyl]-5-methyl-2-phenyl-3-pyrazolin-3-one::MLS000724469::SMR000306063::cid_6614727

SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1C=C1C=c2ccccc2=N1

InChI Key InChIKey=KBKCZYHTRKVJMG-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 43647   

TargetSignal transducer and activator of transcription 3 [702-738,740-752](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43647(4-[(Z)-2-indolylidenemethyl]-5-methyl-2-phenyl-1H-...)
Affinity DataIC50: 229nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2011
Entry Details
PCBioAssay
TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43647(4-[(Z)-2-indolylidenemethyl]-5-methyl-2-phenyl-1H-...)
Affinity DataIC50: 1.82E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43647(4-[(Z)-2-indolylidenemethyl]-5-methyl-2-phenyl-1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43647(4-[(Z)-2-indolylidenemethyl]-5-methyl-2-phenyl-1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43647(4-[(Z)-2-indolylidenemethyl]-5-methyl-2-phenyl-1H-...)
Affinity DataEC50: >5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2011
Entry Details
PCBioAssay