BDBM436201 US10590109, Compound 19

SMILES CC(C)Oc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N

InChI Key InChIKey=YYBQVWKUYCASEH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 436201   

TargetFibroblast growth factor receptor 4 [460-802](Human)
Nanjing Innocare Pharma Tech

US Patent
LigandPNGBDBM436201(US10590109, Compound 19)
Affinity DataIC50: 10nMAssay Description:FGFR4:The in vitro activity of FGFR4 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetFibroblast growth factor receptor 1 [308-731](Human)
Nanjing Innocare Pharma Tech

US Patent
LigandPNGBDBM436201(US10590109, Compound 19)
Affinity DataIC50: 1.00E+3nMAssay Description:FGFR1: The in vitro activity of FGFR1 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2 [400-821](Human)
Nanjing Innocare Pharma Tech

US Patent
LigandPNGBDBM436201(US10590109, Compound 19)
Affinity DataIC50: 1.00E+3nMAssay Description:FGFR2: The in vitro activity of FGFR2 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3 [399-806](Human)
Nanjing Innocare Pharma Tech

US Patent
LigandPNGBDBM436201(US10590109, Compound 19)
Affinity DataIC50: 1.00E+3nMAssay Description:FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent