BDBM43613 2-amino-4-(4-chlorophenyl)-6-methyl-3-pyridinecarbonitrile::2-amino-4-(4-chlorophenyl)-6-methyl-nicotinonitrile::2-amino-4-(4-chlorophenyl)-6-methylnicotinonitrile::2-amino-4-(4-chlorophenyl)-6-methylpyridine-3-carbonitrile::2-azanyl-4-(4-chlorophenyl)-6-methyl-pyridine-3-carbonitrile::MLS000533080::SMR000140518::cid_743778

SMILES Cc1cc(-c2ccc(Cl)cc2)c(C#N)c(N)n1

InChI Key InChIKey=OIADGIDTZVRINS-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 43613   

TargetSignal transducer and activator of transcription 3 [702-738,740-752](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43613(MLS000533080 | 2-azanyl-4-(4-chlorophenyl)-6-methy...)
Affinity DataIC50: 5.90E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2011
Entry Details
PCBioAssay
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43613(MLS000533080 | 2-azanyl-4-(4-chlorophenyl)-6-methy...)
Affinity DataEC50: >5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2011
Entry Details
PCBioAssay
TargetPhotoreceptor-specific nuclear receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43613(MLS000533080 | 2-azanyl-4-(4-chlorophenyl)-6-methy...)
Affinity DataIC50: 3.30E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor corepressor 2 (TRAC-1)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43613(MLS000533080 | 2-azanyl-4-(4-chlorophenyl)-6-methy...)
Affinity DataIC50: 3.26E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay