BDBM4361 (2E)-2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enamide::benzylidenemalononitrile (BMN) deriv. 45

SMILES CC(C)(C)c1cc(\C=C(/C#N)C(N)=O)cc(c1O)C(C)(C)C

InChI Key InChIKey=GUBROJUTOMZSOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4361   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4361((2E)-2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)...)
Affinity DataIC50: 5.50E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4361((2E)-2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed