BDBM4360 (3,4,5,B-Tetrahydroxybenzylidene)malononitrile::2-[hydroxy(3,4,5-trihydroxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 44

SMILES Oc1cc(cc(O)c1O)C(=O)C(C#N)C#N

InChI Key InChIKey=XHBPHEXPTIFHND-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4360   

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM4360(2-[hydroxy(3,4,5-trihydroxyphenyl)methylidene]prop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM4360(2-[hydroxy(3,4,5-trihydroxyphenyl)methylidene]prop...)
Affinity DataKi:  4.50E+3nM IC50: 1.35E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed