BDBM4359 2-[hydroxy(4-hydroxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 43

SMILES Oc1ccc(cc1)C(=O)C(C#N)C#N

InChI Key InChIKey=QVNWVYWUJBWEDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4359   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4359(2-[hydroxy(4-hydroxyphenyl)methylidene]propanedini...)
Affinity DataIC50: 2.30E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4359(2-[hydroxy(4-hydroxyphenyl)methylidene]propanedini...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed