BDBM435848 US10570167, Cpd. # 174::US11034715, Cpd. # 174::US11078228, Example 1
SMILES Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COC(Cc2ccccc2)(C(O)=O)C(O)=O)[C@](O)(C#C)[C@H]1O
InChI Key InChIKey=IWGQJNAZGZERSN-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 435848
Affinity DataIC50: 20nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of bovine CA4More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human CA1More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of CD73 in human plasma incubated for 15 mins in presence of 15N5-AMP by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant mouse CD73 (29 to 549 residues) expressed in CHO cells incubated for 1 hr by malachite green assayMore data for this Ligand-Target Pair