BDBM4357 3-{[4-(1,1-dicyanoprop-1-en-2-yl)phenyl]carbamoyl}propanoic acid::benzylidenemalononitrile (BMN) deriv. 41

SMILES [#6]\[#6](=[#6](\C#N)C#N)-c1ccc(-[#7]-[#6](=O)-[#6]-[#6]-[#6](-[#8])=O)cc1

InChI Key InChIKey=WWDBVULFZSDIRG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4357   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4357(3-{[4-(1,1-dicyanoprop-1-en-2-yl)phenyl]carbamoyl}...)
Affinity DataIC50: 5.00E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed