BDBM435234 US10568874, Example Table 1.7::US10919852, Compound TABLE 1.117::US11135210, TABLE 1.7::US11708326, Compound TABLE 1.117

SMILES CCOc1cc(NC2CCc3c2cccc3-c2cccc(OCCCN3CCC(F)CC3)c2C)c(Cl)cc1CN[C@@H](CO)C(O)=O

InChI Key InChIKey=MTQCWXAPAGNPSX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 435234   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM435234(US10568874, Example Table 1.7 | US10919852, Compou...)
Affinity DataIC50: 253nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W/V...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetProgrammed cell death protein 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM435234(US10568874, Example Table 1.7 | US10919852, Compou...)
Affinity DataIC50: 253nMAssay Description:96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM435234(US10568874, Example Table 1.7 | US10919852, Compou...)
Affinity DataIC50: 253nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W/V...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM435234(US10568874, Example Table 1.7 | US10919852, Compou...)
Affinity DataIC50: 253nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent