BDBM434982 US10584104, Compound of Example 51::US11149013, Compound TY706

SMILES OC(=O)CSc1nnc(Br)n1Cc1ccc(Br)c2ccccc12

InChI Key InChIKey=CPIDEFQXIIQAOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434982   

TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434982(US10584104, Compound of Example 51 | US11149013, C...)
Affinity DataIC50: 81nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434982(US10584104, Compound of Example 51 | US11149013, C...)
Affinity DataIC50: 81nMAssay Description:The IC50 value of URAT1 inhibition for the crystalline form A of TY706 of the present invention was determined according to the following method:Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent