BDBM434894 (4-(2',6'-dimethoxy-4'-methyl- [1,1'-biphenyl]-4-yl)-1H-1,2,3- triazol-1-yl)(2-(pyridin-4- ylmethyl)piperidin-1- yl)methanone::US10583137, Compound 68

SMILES COc1cc(C)cc(OC)c1-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1Cc1ccncc1

InChI Key InChIKey=DUKSUCFKLMTZHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434894   

TargetDiacylglycerol lipase-alpha(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM434894(US10583137, Compound 68 | (4-(2',6'-dimethoxy-4'-m...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetDiacylglycerol lipase-beta(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM434894(US10583137, Compound 68 | (4-(2',6'-dimethoxy-4'-m...)
Affinity DataIC50: 6.00E+3nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent