BDBM434881 (2-Benzylpiperidin-1-yl)(4-(2′,4′,6′-trimethoxybiphenyl-4-yl)-1H-1,2,3-triazol-1-yl)methanone::US10583137, Compound 20

SMILES COc1cc(OC)c(c(OC)c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1Cc1ccccc1

InChI Key InChIKey=SHZTWGAPSPEAQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434881   

TargetDiacylglycerol lipase-alpha(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM434881(US10583137, Compound 20 | (2-Benzylpiperidin-1-yl)...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetDiacylglycerol lipase-beta(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM434881(US10583137, Compound 20 | (2-Benzylpiperidin-1-yl)...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent