BDBM434515 US10562893, Compound 2

SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccc(s3)C(F)F)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C

InChI Key InChIKey=UWDSLMZJTAQBAZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 434515   

TargetTyrosine-protein kinase ITK/TSK(Human)
Gb005

US Patent
LigandPNGBDBM434515(US10562893, Compound 2)
Affinity DataEC50: <10nMAssay Description:ITK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase TXK(Human)
Gb005

US Patent
LigandPNGBDBM434515(US10562893, Compound 2)
Affinity DataEC50: <10nMAssay Description:RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase Tec(Human)
Gb005

US Patent
LigandPNGBDBM434515(US10562893, Compound 2)
Affinity DataEC50:  55nMAssay Description:Tec: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent